Qualipack / Capsule Pharmaceutical Solutions

Capsule Blister
Packing
Machine

Validated blister packing for hard gelatin capsules, soft gelatin softgels, HPMC vegetarian capsules, and liquid-filled capsules. Capsule-specific orientation feeder, gentle pneumatic handling to prevent shell damage, and the same 21 CFR Part 11 compliance platform as our tablet blister machines.

Capsule Orientation FeederGentle Pneumatic HandlingHard / Soft / HPMC Capsules200–350 Blisters/Min
Capsule blister packing machine hard soft gelatin
90+
Capsule Lines Installed
350
Blisters/Min Max
30+
Countries
100%
Vision Inspected
Product Coverage

Capsules We Blister

From standard size-00 hard gelatin to small pediatric size-4 and large softgel formats — every capsule type on validated handling.

💊
Hard Gelatin Capsule
Standard size 0–4, 2-piece
🟢
Soft Gelatin (Softgel)
Liquid-filled, oval
🌱
HPMC Vegetarian
Plant-based, vegan certified
💧
Liquid-Filled Hard Capsule
Hard shell, oil/liquid fill
🎨
Coated Capsule
Enteric, sustained-release
Branded Capsule
Logo / color combinations
🟡
Vitamin Softgel
Fish oil, vitamin E supplement
🔵
Pediatric Capsule
Size 3–4 small format
🟠
Color-Coded Pharma
Body / cap color differentiation
Clear Gelatin
Visible fill content
🟤
Brown / Amber Capsule
Light-sensitive API
🎯
Generic Pharma
High-volume commodity
Pharma Packaging Formats

Pharmaceutical Packaging Formats

From primary blister/vial to retail carton and shipper — every pharma format on validated equipment.

Sachet
Powder / granule
Single-dose sachet for sachet medicines
4-sideFoil
Stick Pack
Powder / granule
Slim stick for OTC granule medicines
Multi-lane
Pouch
Liquid / granule
Doypack for oral suspension
SpoutTamper
Bottle (PET / HDPE / Glass)
10ml – 1L
Syrup, suspension, OTC
Child-resistantDropper
Vial / Ampoule
1ml – 100ml
Injectable / parenteral primary container
GlassRubber stopper
Carton (Folding)
Retail
Blister-into-carton, leaflet insertion
LeafletBraille
Shipper Case
Distribution
Corrugated outer with serialized aggregation
SSCCSerialized
Machine Solutions

Capsule Blister Packing Solutions

Three configurations covering hard gelatin high-volume, soft gelatin specialty, and combination capsule+tablet flexibility.

Hard capsule PVC Alu blister machine
HARD CAPSULE BLISTER
Most Popular for Hard Gelatin

Hard Capsule PVC/Alu Blister Machine

Hard Gelatin & HPMC Capsules · Pharma / Nutraceutical · 200–350 Blisters/Min

The standard for hard gelatin and vegetarian capsule blister packing — PVC/Alu thermoform with capsule-specific feeding. Vibratory orientation feeder ensures every capsule is body-down in the pocket (proper presentation for the patient when blister is opened). 100% vision inspection of orientation + presence. Gentle pneumatic placement avoids shell cracking on hard capsules.

200–350 blisters/min
Size 00 to size 4
PVC/Alu thermoform
Orientation + vision
Request Quote →
Softgel Alu Alu cold-form blister machine
SOFTGEL ALU/ALU
Softgel Specialty

Softgel Alu/Alu Cold-Form Blister

Soft Gelatin Capsules · Fish Oil · Vitamin E · CoQ10 · Fat-Soluble Pharmaceuticals

Cold-form Alu/Alu blister for softgels — the gold standard for oxidation-sensitive fish oil, vitamin E, and fat-soluble drug formulations. Cold-formed aluminum laminate provides total moisture and oxygen barrier essential for softgel content stability. Gentle vacuum-cup pickplace prevents shell deformation common with rough handling.

100–200 blisters/min
Softgel oval / oblong
Alu/Alu cold-form
Complete O2/moisture
Request Quote →
Combination capsule tablet blister
CAPSULE+TABLET COMBO
Tablet + Capsule Combo

Combination Capsule/Tablet Blister Platform

Multi-Product Pharma · Capsule + Tablet SKUs Mixed · CMO Flexibility

Flexible blister platform supporting BOTH capsules (any type) AND tablets on the same machine — change format set and feeder in 90 minutes. Ideal for pharma manufacturers and CMOs running mixed capsule + tablet product portfolios. Common machine controls, shared FAT/SAT, single operator skill base across all SKUs.

150–300 blisters/min
Capsule + Tablet
90 minutes
Multi-product pharma
Request Quote →
Complete Production Line

Complete Pharma Packaging Line

From primary blister/vial to serialized, leafleted, cased retail unit — fully validated under GMP.

💊
1
Primary Pack
Blister / vial / sachet
👁️
2
Inspection
Vision check 100%
🏷️
3
Print & Code
LOT / EXP / serialization
📄
4
Cartoning
Leaflet insertion + close
5
Track & Trace
DataMatrix verification
📦
6
Case Pack
Aggregated SSCC outer
Challenges & Solutions

Common Challenges in Capsule Blister Packing

😤 What Goes Wrong
📍
Capsules in wrong orientation in pocket — patient receives capsule cap-down, looks unprofessional, complaint risk
💔
Hard gelatin shells crack under rough mechanical placement — visible damage rejected at vision, yield loss
🛡️
Softgels lose plasticizer through PVC barrier — bottles arrive deformed or stuck together after 12 months
📋
21 CFR Part 11 audit fails on electronic-record compliance — FDA Form 483 issued, exports blocked
🔄
Format change between size 0 and size 2 capsules takes 3+ hours — every size needs different feeder channels
👁️
Color-coded capsules (red/white body and cap) flip orientation undetected — wrong-orientation patient confusion
OUR ANSWER
✅ Our Solutions
Vibratory orientation feeder with body-down singulation + vision verification — every capsule in correct orientation
Gentle pneumatic vacuum-cup pickplace (not mechanical pusher) — zero shell-crack damage on hard capsules
Alu/Alu cold-form blister for softgels — total barrier prevents plasticizer migration and content oxidation
21 CFR Part 11 compliant PLC with audit trail, e-signature, password hierarchy + full validation package
Servo-driven quick-change format set + size-specific feeder channels supplied + PLC recipe storage
Color vision inspection at orientation station + auto-reject of flipped or mismatched cap/body pairings
Customization Capabilities

Customization & Validation Capabilities

Pharma machines aren't bought — they're validated. We supply full IQ/OQ/PQ documentation, 21 CFR Part 11 compliant controls, and serialization integration as standard.

GMP-compliant, validated, serialization-ready

Every pharma machine ships with full design qualification documentation, material certificates, electrical schematics, and IQ/OQ protocol templates. Track-and-trace serialization (GS1 DataMatrix, parent-child aggregation) is built in, not bolted on.

Engineering To Spec
GMP-Validated
Primary Format
Blister / vial / sachet
PVC/Alu blister: standard cold or thermoform
Alu/Alu blister: moisture/oxygen barrier
Glass vial: 2R, 6R, 10R, 30R standard
Stick / sachet: for OTC granules
Fill Range
Dose accuracy
Tablet count: per blister cavity, vision verified
Capsule count: with feeder + orientation
Vial liquid: 0.5ml – 100ml, ±1%
Vial powder: auger dose with weight verify
Contact Material
GMP-grade
SUS316L electropolished, Ra ≤ 0.4μm
Class 100 (ISO 5) isolator / RABS optional
FDA-grade rubber, PTFE seals only
Material certificates 3.1 traceable
CIP / SIP
Validated cleaning
CIP fully validated per riboflavin protocol
SIP capability for aseptic vial filling
Sampling ports at all critical points
Cleaning verification swab/rinse protocols supplied
Servo & Speed
Throughput
Blister: 200–400 blisters/min
Vial: 6,000 – 30,000 vials/hr
Sachet: up to 1,200/min (multi-lane)
Servo-driven indexing for accurate placement
Control & Serialization
21 CFR + GS1
21 CFR Part 11 compliant audit trail
GS1 DataMatrix printing + 100% verification
Parent-child aggregation to SSCC pallet
EPCIS export for EU FMD / DSCSA compliance

Send us your product sample — we'll size the machine to your exact recipe, viscosity, particle size, and target container.

Request Custom Spec
Why Choose Us

Why Capsule Manufacturers Choose Qualipack

Capsule-specific orientation, gentle handling, and the GMP documentation pharma regulators demand.

Pharma packaging machine GMP quality
100%
Capsule orientation vision-verified — every pocket inspected before sealing
📍

Body-Down Orientation

Vibratory feeder with vision verification — patient opens the blister to a properly-oriented capsule every time.

💔

Gentle Pneumatic Placement

Vacuum-cup pickplace replaces mechanical pusher — zero shell cracking on hard gelatin capsules.

🛡️

Softgel-Safe Barrier

Alu/Alu cold-form blister preserves softgel plasticizer and prevents oil oxidation — full 24-month stability.

📋

21 CFR Part 11 Compliant

Same FDA-validated PLC platform as our tablet machine — full audit trail and e-signature support.

🔄

Quick Capsule Size Change

Size 00 to size 4 changeover in 90 minutes with stocked feeder channels and PLC recipe recall.

🌍

Capsule Industry Experience

90+ capsule blister lines from generic pharma to vitamin softgel exporters to specialty HPMC vegan brands.

Technical Highlights

Technical Features

Engineering and validation specs for pharma quality assurance teams.

📍

Orientation Feeder

Vibratory + vision body-down verification

💔

Pneumatic Pickplace

Vacuum-cup gentle, no shell crack

👁️

100% Vision Check

Orientation + presence + color verified

🛡️

Alu/Alu Cold-Form

Total barrier for softgel oxidation control

📋

21 CFR Part 11 PLC

Audit trail, e-signature, validated

📐

Size Quick-Change

Size 00–4 feeder channels in 90 min

🔍

GS1 DataMatrix

Serialization print + verify + aggregate

📡

EPCIS Export

DSCSA / EU FMD / NMPA data export ready

Pharmaceutical packaging machine validated equipment
Customer Cases

Capsule Brand Success Stories

Real results from hard capsule pharma manufacturers, softgel specialists, and HPMC vegan supplement brands.

Indian hard capsule generic pharma
IndiaGeneric Pharma

Indian Manufacturer Cuts Capsule Crack-Loss from 3% to 0.1%

An Indian generic pharma manufacturer was losing 3% of hard gelatin capsules to shell cracking during mechanical pickplace — about $180K/year in scrap. Replacing the mechanical pusher with vacuum-cup pneumatic placement cut shell-crack rejects to 0.1%, recovering the vast majority of that loss.

−97%
Capsule shell-crack rejects reduced to 0.1%
EU fish oil softgel exporter
NorwayFish Oil Softgel Brand

Norwegian Fish Oil Brand Extends Softgel Shelf to 36 Months

A Norwegian premium fish oil brand was getting customer complaints about softgels sticking together by month 18 — PVC barrier wasn't preventing plasticizer migration. Switching to Alu/Alu cold-form blister extended verified stability to 36 months, supporting longer distribution channels and higher-margin export markets.

36mo
Verified softgel stability — up from 18 months
US vegan HPMC capsule supplement
USAVegan Supplement Brand

US Vegan Brand Wins Retail with HPMC Capsule Quality

A US plant-based supplement brand expanding into mainstream retail (Whole Foods, Sprouts) needed pharmaceutical-grade blister presentation for HPMC vegetarian capsules. Vision-verified body-down orientation + premium card design + tamper-evident perforations secured the retail listings against established competitors.

12
New national retail chain listings secured
FAQ

Frequently Asked Questions

What buyers most often ask before purchasing.

How does the capsule orientation feeder work?

+

Vibratory bowl feeder pre-sorts capsules into a single-file track. The orientation station uses a profile detector (mechanical or optical) to identify body vs. cap end of each capsule. Mis-oriented capsules are diverted to a return loop and re-fed. Properly oriented capsules drop into the blister pocket body-down (the standard pharma presentation when patient opens the blister). Vision then verifies orientation in the pocket before seal. Result: <0.05% mis-oriented capsules in finished product.

Can the machine handle softgels and hard capsules on the same line?

+

Yes — but with format change. Softgels and hard capsules have very different shapes (softgel is typically oval/oblong, hard capsule is cylindrical with rounded ends). Different blister pocket geometry, different feeder channels, different vision tuning. Format change between softgel and hard capsule SKUs is typically 90 minutes including cleaning. Both capsule types share the same machine platform and controls.

Are HPMC vegetarian capsules handled differently than gelatin?

+

HPMC (hydroxypropyl methylcellulose) capsules are slightly more rigid than gelatin but otherwise handle similarly on our equipment. Same orientation feeder, same blister pocket size, same vision inspection. The main difference is at the cellulose-supplier level — HPMC capsules from different suppliers vary slightly in dimensions, so we test your specific capsule supplier during sample trial to verify the feeder channel and pocket fit. Equipment-side, no special accommodation needed.

What about color-coded capsules with body and cap in different colors?

+

Common in pharma for product differentiation (e.g., red body + white cap for one strength, green body + white cap for another). Our vision system tunes to verify both body color AND cap color are correct in each pocket — auto-rejects mismatched or flipped capsules. For high-stakes prescription products we also recommend an additional color verification at carton-pack stage as defense-in-depth.

Why Alu/Alu for softgels specifically?

+

Softgels contain a liquid or semi-solid fill (typically oils — fish oil, vitamin E, CoQ10, fat-soluble drug formulations). The oil migrates plasticizer out of the gelatin shell over time, causing softgels to stick together or harden. PVC barrier slows this but doesn't stop it. Alu/Alu cold-form provides a complete barrier — no plasticizer loss, no oxygen penetration, no light. Extends softgel stability typically 18 months → 36 months. Worth the additional cost for premium softgel brands.

Do you support liquid-filled hard capsules (LFHC)?

+

Yes — LFHC is a growing category where liquid or semi-solid fill is dosed into a sealed hard gelatin or HPMC capsule. The sealed capsule handles like any hard capsule on the blister machine (same orientation, same vision, same pocket). The liquid-filling and sealing is upstream — we can refer you to capsule-filling equipment suppliers we partner with for that part of the process if not already in place.

What's the typical changeover time between capsule sizes?

+

Size change (e.g., size 0 to size 2): 60–90 minutes including feeder channel change, pocket tooling change, PLC recipe load, and brief test run. Quick-change tooling is supplied with the machine for each capsule size you specify at order. PLC recipe storage saves all parameters (orientation thresholds, vision tuning, fill speed) per SKU. After a few cycles the operator changeover skill builds and 90 minutes is achievable consistently.

Can you supply complete capsule pharma lines?

+

Yes — typical complete capsule pharma line: capsule polishing → blister machine → checkweigher → cartoner with leaflet insertion → tamper-seal → case packer (with aggregation) → palletizer. All synchronized via unified PLC. We partner with capsule-filling equipment OEMs for the upstream filling and sealing step if needed. Single point of accountability for the secondary packaging from capsule polishing to palletized case.

One Stop Packaging Machinery Solutions

Sourcing packaging machines from Qualipak is simple and cost-effective.